Warning signs include sudden, intense pain in the right upper abdomen or center of the abdomen that may radiate to the right shoulder or back, nausea and vomiting with abdominal pain, fever and chills, jaundice, or clay-colored stools
The study included an adequate number of subjects in the mild, moderate, severe impairment, or ESRD groups, while comparing with an appropriately baseline-matched and sized control reference group
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